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Article Name :
OLIVE OILS IMMUNOMODULATORY EFFECT IN PROTECTION THE LIVER AND HEART TISSUES IN RATS FED WITH HIGH CHOLESTEROL DIETS .
Author Name :
MABROKA H. HEMIDA, AMAL A.E. IBRAHIM , RASHA M. E. BAHNSAWY , MONA R. AL-SHATHLY
Publisher :
Ashok Yakkaldevi
Article Series No. :
ROR-610
Article :
Author Profile
Abstract :
Due to our busy lives and rely on the consumption of junk food, leading to increase cholesterol levels in blood, that causes heart diseases. And according to the global trend in reduction of using medications that cause imbalance in the body's functions and the trend to use natural materials in the treatment of diseases, as they have no side effects on human health if used as doctor describe. The question is: Does the quality of olive oil have a role in its hypocholesterolamic effect? The present study aimed to determine the protective role of tow types olive oils on heart and liver tissues in rats fed on high cholesterol diet. Hypercholesterolaemia induced in male albino rats, by feeding on high cholesterol diets. Hypercholesterolaemia characterized by significant increase in the averages of total cholesterol and triglycerides, LDL and decreased levels of HDL. The study includes histological, histopathological and immunological studies, which delineated increase of fat droplets, degenerated hepatocytes, and increase in CD45RO expression in the hepatic tissue. Treatment with olive oils reduced the serum levels of cholesterol, triglycerides, LDL and increased the HDL levels. The histological picture of liver and heart reported improvents, and decrease in CD45RO expression in liver tissue.
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